PubMed:: "Lymphoma, Large B-Cell, Diffuse"[Mesh] OR (lymphoma*[tiab] AND (large-cell[tiab] OR large b-cell[tiab]) AND diffuse[tiab]) OR (("Lymphoma, Non-Hodgkin"[Mesh] OR (lymphoma*[tiab] AND (non hodgkin*[tiab] OR nonhodgkin*[tiab]))) AND (aggressive[tiab] OR high grade[tiab] OR advanced stage[tiab] OR intermediate grade[tiab]));; Embase.com:: 'large cell lymphoma'/exp OR (lymphoma*:ab,ti AND ('large cell':ab,ti OR large) AND 'b cell':ab,ti AND diffuse:ab,ti) OR ('nonhodgkin lymphoma'/exp OR (lymphoma*:ab,ti AND ('non hodgkin':ab,ti OR nonhodgkin*:ab,ti)) AND (aggressive:ab,ti OR high AND grade:ab,ti OR advanced AND stage:ab,ti OR intermediate) AND grade:ab,ti);; Cochrane Library:: (lymphoma*:ti,ab,kw AND ("non hodgkin*":ti,ab,kw OR nonhodgkin*:ti,ab,kw) AND (aggressive:ti,ab,kw OR "high grade":ti,ab,kw OR "advanced stage":ti,ab,kw OR "intermediate grade":ti,ab,kw))